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1.
Journal of Pharmaceutical Negative Results ; 13:741-751, 2022.
Article in English | EMBASE | ID: covidwho-2156349

ABSTRACT

Background: Over the past 1.5 years significant advances in the treatment of Covid-19 have emerged. Please reword to reflect this change. Among the variety of suggested materials to aid patients regarding COVID-19, we chose Vitamin C, as it offers antioxidant functions and beneficial effects on the immune system. In this study, we aim to review the function and application of Vitamin C in body health during COVID-19 infection and elucidate the controversies around its efficacy against coronavirus infection. Method(s): We meticulously searched the relevant articles (n = 153) from PubMed, Scopus, Embase, databases according to the aimed keywords (COVID-19, Vitamin C, Treatment, Management). Result(s): Supportive supplements are reasonable methods in countering the pandemic along with clinical therapy. Furthermore, Vitamin C helps prevent septic shock and further organ failure. Discussion(s): We believe that our review demonstrates the highlights of one of the most important supplements in the disease relief. Copyright © 2022 Wolters Kluwer Medknow Publications. All rights reserved.

2.
Eur Rev Med Pharmacol Sci ; 26(6): 2188-2195, 2022 03.
Article in English | MEDLINE | ID: covidwho-1776798

ABSTRACT

OBJECTIVE: COVID-19 disease can cause damage to various organs, especially the kidneys, so the main purpose of this study was to investigate the effect of different aspects of kidney damages caused by COVID-19 in a narrative review study. MATERIALS AND METHODS: To conduct this study, all studies related to the topic under discussion during 2020-2021 were reviewed by systematic search in internationally available databases including Web of Science, Science Direct, Scopus, PubMed, and Google Scholar. Finally, 42 completely related studies were selected to extract the results. RESULTS: The prevalence of acute kidney injury (AKI) varies in different parts of the world and has reached almost 70%. The results showed that, in general, a high percentage of COVID-19 patients had symptoms of renal dysfunction at the time of hospitalization, and the most important of these symptoms were proteinuria, hematuria, and increased serum creatinine. Based on the results, it can be said that AKI most likely occurs early in the disease and in parallel with lung damage. So far, various drugs have been used to control or treat COVID-19 and reduce inflammation in patients. Regardless of their usefulness, some of these drugs may adversely affect kidney function and damage the kidneys. The study results show that chronic kidney disease (CKD) in COVID-19 patients plays a minor role in renal replacement therapy (RRT), and the highest impact on the need for RRT is COVID-19. CONCLUSIONS: This study showed that one of the major negative effects of COVID-19 on the human body is kidney damage, among which acute kidney injury (AKI) is the most important one. In addition, the prevalence of AKI due to COVID-19 varies widely around the world. Although any medication may damage the kidneys, COVID-19 or anti-inflammatory drugs are not an exception to this rule, but more research is needed to gain more information.


Subject(s)
Acute Kidney Injury , COVID-19 , Acute Kidney Injury/diagnosis , Acute Kidney Injury/epidemiology , Acute Kidney Injury/therapy , Humans , Kidney , Proteinuria , Renal Replacement Therapy/adverse effects
3.
Kybernetes ; 2021.
Article in English | Scopus | ID: covidwho-1437889

ABSTRACT

Purpose: The current pandemic will introduce many novel policies, adaptations, innovations and procedures by innovative human resource (HR) creativity. In particular, information technology (IT) implementation is a field that needs more significant focus and a wider range of creative interventions. The author would undoubtedly see a more human-focused approach to HR management (HRM) in the post-coronavirus disease 2019 (post-COVID-19) era, where enterprises and workers have had to reinvent themselves in a brief amount of time drastically. Following the nationwide lockdown caused by COVID-19, many companies were pushed to opt for remote working, which presents both difficulties and benefits for workers and employers. So the purpose of this study is to investigate some key consequences resulting from COVID-19’s effect on multiple HRM roles, how technology is empowering and fostering HRM, informative forecasts based on how organizations are coping and finally, the path in the post-pandemic environment. Design/methodology/approach: The COVID-19 epidemic has had a significant effect on every area of the global economy. It has had severe implications for public institutions and raises particular questions for medical schools. The emergence of COVID-19 has disrupted many activities and requires intense and prompt attention from medical educators. So, HR leaders now face the difficult task of managing the interests of workers and their corporations. The outbreak of COVID-19 has proved that this is not just a difficult time but rather a testing time for companies across the globe to check and ensure how swiftly they adapt themselves by thinking and planning differently. An enterprise evolves with nature, and change is unavoidable if performance and productivity are to improve. Changes in structure, technology and priorities are overgrowing, posing big obstacles to leaders. Corporations worldwide have looked to technology to pursue creative solutions to some of the world’s most pressing problems. This study provides a review of articles related to the role of technology in HRM in the COVID-19 period. The analyzed articles are divided into three groups, including articles related to the role of information communication technology, cloud computing and teleworking in HRM in the COVID-19 era. Also, the most important key challenges are collected, and solutions are provided for them. Findings: In times of trouble, authentic leadership shines through. The actions of pioneering HR leaders throughout the COVID-19 epidemic will significantly affect their respective organizations. When COVID-19 expanded around the world, HR agencies made their workers’ health and welfare a top priority. HRM’s long-term sustainability can be dictated by how they deal with the current crisis. Web-based solutions, such as cloud computing, will also address a vital resource allocation gap. It illustrates the possible efficacy of patient-oriented, web-based applications built on result-driven design, which continues to be validated by more testing and assessment. Many studies have emphasized business innovation as a necessity due to changes in the environment and various challenges and requirements facing businesses. The challenge of observing social distance and limiting face-to-face business services is the challenge of the COVID-19 pandemic era. Research limitations/implications: This study could entail a joint international collaboration initiative among research centers, allowing information about COVID-19 impacts to be shared more easily. It will favor a worldwide policy to find a response to the epidemic but still address cultural and social issues. Practical implications: The survey concludes that, whenever possible, employers and medicals should explore remote working opportunities in all industries to alleviate uncertainty and improve employee psychological well-being. The facilitating considerations and problems are often addressed in order to supply practical views for developing cloud-based solutions. Originality/value: This research ims to lead to the advancement of scientific knowledge in the HRM area through the use of IT-based technology. It allows businesses to reinvent HRM techniques to save money and maximize efficiency without compromising their employees’ life quality and well-being. More in-depth studies at various pandemic stages would yield more valuable insights into HRM’s emerging position. © 2021, Emerald Publishing Limited.

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